Glock has now introduced two of their most common pistols set up for reflex optics. I got a chance a shoot the Glock 19 MOS yesterday and I like it. Shooting a pistol with a red dot reflex optic takes some getting used to but as many others have said, it probably is the wave of the future.
My only problem with Glocks is that I have small hands and they don't quite fit me that well. I'll have to work on that.